MOTS-c 10MG
$32.00MG
Research suggests MOTS-c may help cells produce energy more efficiently and support healthy metabolism. Studies show this mitochondrial peptide could improve how the body uses sugar, reduce inflammation, and support healthy aging. Scientists are especially excited about its potential to enhance exercise performance and protect heart health. This lyophilized powder requires reconstitution with bacteriostatic water before use.
In stock
Overview
Think of MOTS-c as your cells’ energy management consultant-a specialized peptide that emerges from the mitochondria (your cellular power plants) to help optimize how your body uses and distributes energy. Just as a smart thermostat learns to regulate your home’s temperature efficiently, MOTS-c appears to help cells adapt their energy usage based on current needs, potentially improving everything from metabolism to stress response.
Discovered relatively recently in the world of peptide research, MOTS-c represents an exciting frontier in understanding how our mitochondria communicate with the rest of our cells. This 16-amino acid peptide has shown remarkable promise in laboratory studies for its ability to influence metabolic pathways, cellular aging, and overall energy homeostasis.
Key Characteristics
MOLECULAR PROFILE
- Formula: C101H152N28O22S2
- Weight: 2174.6 g/mol
- CAS: 1627580-64-6
- Sequence: 16 amino acids
PHYSICAL PROPERTIES
- Form: White to off-white lyophilized powder
- Solubility: Water-soluble
- Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
- Stability: Stable when properly stored
How It Works
MOTS-c operates like a master switch for cellular metabolism, activating multiple pathways that help cells use energy more efficiently. When released from mitochondria, this peptide travels throughout the cell and even into the bloodstream, where it can influence metabolism on a whole-body level.
Primary Mechanisms
AMPK Pathway Activation
Acts as your cells’ fuel gauge sensor. When AMPK is activated, cells become more efficient at burning fat for energy and maintaining healthy insulin sensitivity.
Metabolic Regulation
Influences glucose uptake from the bloodstream and optimizes cellular energy utilization across all systems.
Secondary Effects
Gene Expression Modulation
Influences gene expression related to metabolism and aging, potentially helping cells maintain their youthful function longer.
Multi-Level Approach
This comprehensive mechanism makes MOTS-c a fascinating subject for metabolic and longevity research.
Research Findings
Laboratory investigations have revealed multiple areas where MOTS-c demonstrates significant research potential.
Metabolic Health Enhancement
- Exercise-mimetic properties demonstrated in 2024 studies
- Improves insulin sensitivity through AMPK activation
- Reduces cognitive decline in aging models (2023)
- Enhances mitochondrial biogenesis and oxidative capacity
- Increases glucose uptake independent of insulin
- Better blood sugar control in high-fat diet models
- Reduced fat accumulation in research subjects
- Potential applications in metabolic disorder research
Cellular Energy Optimization
- Promotes burning of fatty acids for energy
- Increased ATP production in treated cells
- Improved endurance in animal models
- More efficient energy utilization overall
Neuroprotective Properties
- Protection from oxidative stress
- Reduced age-related neuronal damage
- Improved cognitive function in models
- Decreased neuroinflammation markers
Longevity and Healthy Aging
- Studies show potential for extending healthspan in research models.
- Extended lifespan in certain models
- Activation of longevity-associated genes
- Protection from cellular stress
- Natural decline with age makes it a key target
Cardiovascular Support
- Protection of heart tissue from damage
- Reduced inflammation in blood vessels
- Better heart muscle performance
- Improved cardiovascular function markers
Potential Side Effects in Research
Metabolic Monitoring
Potential changes in blood glucose levels requiring monitoring in diabetic research models
Drug Interactions
Limited data on interactions with other compounds or medications
Administration Effects
Possible mild injection site reactions in animal studies
Long-term Considerations
Theoretical concerns about long-term metabolic adaptations that require further investigation
References
- MOTS-c: A mitochondrial-encoded peptide in aging and disease. Ageing Res Rev. 2024.
- Exercise-mimetic properties of MOTS-c in metabolism. J Mol Med. 2024.
- MOTS-c reduces insulin resistance and cognitive decline. Nat Commun. 2023.
- Mitochondrial-derived peptides in cardiovascular disease. Front Cell Dev Biol. 2023.
- MOTS-c is an exercise-induced mitochondrial regulator of physical performance. Am J Physiol. 2021.
- MOTS-c: Novel mitochondrial-derived peptide in muscle and fat metabolism. Front Endocrinol. 2019.
- Mitochondrial-derived peptides associated with aging and longevity. Nat Commun. 2018.
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis. Cell Metab. 2015.
Related products
