Description
Overview
Bacteriostatic Water represents a critical component in peptide research infrastructure. This carefully formulated solution combines ultra-pure water with benzyl alcohol to create an environment that inhibits bacterial growth while maintaining the integrity of dissolved compounds. The 0.9% benzyl alcohol concentration is precisely calibrated to provide antimicrobial protection without interfering with most research compounds. This balance makes bacteriostatic water the gold standard for reconstituting lyophilized peptides, ensuring both stability and sterility throughout the research process.
This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
COMPOSITION
- Base: Sterile Water for Injection (USP)
- Preservative: 0.9% Benzyl Alcohol
- pH: 4.5-7.0
- Osmolality: 0 mOsm/kg
PHYSICAL PROPERTIES
- Appearance: Clear, colorless liquid
- Sterility: 0.22μm filtered
- Endotoxin: <0.25 EU/mL
- Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
How It Works
Bacteriostatic water functions through multiple protective mechanisms:
Antimicrobial Action
Benzyl Alcohol Mechanism
Disrupts bacterial cell membranes and denatures proteins
Static vs Cidal
Inhibits bacterial growth (bacteriostatic) rather than killing (bactericidal)
Broad Spectrum
Effective against most common laboratory contaminants
pH Stability
Maintains antimicrobial activity across pH range
Peptide Compatibility
Non-reactive
Does not interact with most peptide structures
Stability Enhancement
Helps maintain peptide integrity during storage
Multiple Withdrawals
Allows repeated access without contamination risk
Research Applications
Bacteriostatic water serves multiple critical functions in research:
Peptide Reconstitution
Primary application in peptide research:
- Dissolves lyophilized peptides while maintaining structure
- Preserves biological activity of sensitive compounds
- Enables accurate dosing and dilution
- Compatible with most research peptides
Storage Solutions
Extended stability for research compounds:
- Allows storage of reconstituted peptides for weeks
- Prevents bacterial contamination during storage
- Maintains sterility through multiple uses
- Reduces waste from single-use preparations
Laboratory Standards
Meeting research quality requirements:
- USP-grade water ensures consistency
- Low endotoxin levels for sensitive assays
- Validated sterility for reproducible results
- Documented quality control parameters
Best Practices
Optimal use in research settings:
- Use aseptic technique for all withdrawals
- Store reconstituted peptides as recommended
- Label vials with reconstitution date
- Discard if any cloudiness or particles appear
Important Considerations
Key factors for optimal bacteriostatic water use:
Temperature Sensitivity
Store at recommended temperature to maintain sterility
Volume Considerations
Calculate appropriate reconstitution volumes
Compatibility Check
Verify peptide compatibility with benzyl alcohol
Expiration Dating
Monitor expiration and discard when expired
Proper use of bacteriostatic water is essential for maintaining research integrity and reproducibility.
IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.
References
- United States Pharmacopeia. “Bacteriostatic Water for Injection.” USP Monographs.
- Meyer BK, et al. “Antimicrobial preservative use in parenteral products: Past and present.” J Pharm Sci. 2007.
- Nema S, et al. “Excipients and Their Role in Approved Injectable Products.” PDA J Pharm Sci Technol. 2011.
- FDA Guidance. “Container Closure Systems for Packaging Human Drugs and Biologics.” 1999.
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